ABSTRACT
To date, there are still very few reports on benign-tumor cases based on East Asian skeletal series, even though other regions and continents have been well represented. In our study on the Joseon Human Skeletal Series, we identified benign bone tumors in two skeletons (cases Nos. 75 and 96). Our radiological analyses showed both cases to be homogeneous sclerotic bone masses aligned with the cranial vault suture. In a subsequent series of differential diagnoses, we determined both cases to be osteoma, the most common bone-tumor type reported for archaeological samples. Our study is the osteoarchaeological basis for this, the first-ever report on benign bone neoplasm in a pre-modern East Asian population.
Subject(s)
Humans , Asian People , Bone Neoplasms , Diagnosis, Differential , Korea , Osteoma , Paleopathology , Skeleton , Skull , SuturesABSTRACT
Analysis of ancient DNA (aDNA) extracted from Ascaris is very important for understanding the phylogenetic lineage of the parasite species. When aDNAs obtained from a Joseon tomb (SN2-19-1) coprolite in which Ascaris eggs were identified were amplified with primers for cytochrome b (cyt b) and 18S small subunit ribosomal RNA (18S rRNA) gene, the outcome exhibited Ascaris specific amplicon bands. By cloning, sequencing, and analysis of the amplified DNA, we obtained information valuable for comprehending genetic lineage of Ascaris prevalent among pre-modern Joseon peoples.
Subject(s)
Adult , Animals , Female , Humans , Male , Ascariasis/diagnosis , Ascaris/classification , Base Sequence , Cytochromes b/genetics , DNA Primers/genetics , DNA, Helminth/genetics , DNA, Mitochondrial/genetics , Fossils/history , History, Ancient , Molecular Sequence Data , Mummies/history , Ovum/chemistry , Phylogeny , RNA, Ribosomal, 18S/geneticsABSTRACT
The author's name and the institutional affiliation of the authors were published incorrectly.